Idiopathic Thrombocypenic Purpura (ITP)


Pathophysiology

Diagnosis

Treatment

  1. Treatment is reserved for severe bleeding with platelets <50,000/mm3 or platelet count <10,000/mm3 without bleeding.
  2. For children:
  3. Acute
  4. Chronic: Prednisone 1mg/kg/day, splenectomy, +/- immunosuppression (cyclophosphamide, azathioprine or vincristine), danazol 200 mg PO tid, IV IgG 0.4 g/kg IV qd x 5d