Syphilis in Pregnancy
- Given that perinatal transmission in mothers with 1 or 2
syphilis is 50%, universal screening for serology (RPR or VDRL) is
recommended at the first prenatal visit.
- Penicillin G benzathine (Bicillin L-A) 2.4 million Units IM
- Desensitization to penicillin is recommended in
- Perinatal death, preterm birth (especially in the setting of a
Jarisch-Herxheimer reaction), congenital anomalies, IUGR