|Pregnant||(+) Chicken Pox||→||Treatment is Similar to that of non-pregnant pts.
- Zovirax (Acyclovir) 800 mg PO 5x/day x 7 days
|Post-Exposure||→||(+)Hx of VZV
(-)Hx of VZV
VariZIG (passive immunization): 125 units/10 kg body weight
given IM, with a maximum dose of 625 units (5 vials)
- IVIG — For pregnant women who cannot receive VariZIG within 10 days of exposure, clinicians may choose either to administer a single dose of intravenous IVIG at 400 mg/kg
closely monitor for signs and symptoms of varicella and institute treatment with acyclovir if illness occurs.
- There are no data on whether acyclovir is beneficial in reducing the risk of varicella after exposure during pregnancy.
|(+) Rash||- Zovirax (Acyclovir) 800 mg PO 5x/day x 7 days|
50. A 35-year-old primigravid schoolteacher awakens with a rash
clinically consistent with varicella early in the 38th week of her
pregnancy. She had a negative varicella titer early in her pregnancy. The
clinical course is mild and all vesicles have either crusted over or healed
1 week later. She has an uncomplicated labor and vaginal delivery at 40
weeks gestation, and delivers a healthy-appearing male.
Of the following options, which one is the most appropriate initial management for the newborn?
A) Intravenously administered varicella immune globulin
B) A weight-appropriate dose of intravenous acyclovir (Zovirax)
C) Varicella vaccine
D) Combination treatment with varicella vaccine, intravenous acyclovir, and varicella immune globulin
E) Close observation only