Arsenic Toxicity


Diagnosis
  1. Symptoms
  2. PE
  3. Diagnostic testing

Pathophysiology

  1. Trivalent metal: binds sulfhydryl groups; inhibits oxidative phosphorylation; mulisystem disease
  2. Kinetics

Treatment

  1. ABC's, IV, O2, monitor
  2. Antidotes: chelation
  3. Decrease absorption
  4. Increase elimination
  5. Hypotension

Disposition

  1. Admit