Ecstasy (MDMA)


Pathophysiology

  1. Amphetamine derivative that releases catecholamines (dopa, norepi, serotonin) and blocks reuptake, MAOI
  2. Risk factors for toxicity
  3. Kinetics
  4. Morbidity/mortality

Diagnosis

  1. Symptoms
  2. PE
  3. Diagnostic testing

Treatment

  1. ABCs, IV, O2, monitor (supportive care) see sympathomimetic OD
  2. Decrease absorption
  3. Hyperthermia
  4. Agitation
  5. Hypertension
  6. Rhabdomyolysis
  7. Seizures
  8. See SIADH, serotonin syndrome