Inhalants Toxicity


Inhaled drugs of abuse are a diverse group of substances (see Table 6.19) that
are inhaled for their euphoric effects. Toxicity is unique to each substance.

HYDROCARBONS
Found in readily available household products, typically in the propellant; inhaled via three common routes:

MECHANISM/TOXICITY

SYMPTOMS/EXAM

TREATMENT

Inhalant Toxicity
Hydrocarbons (gasolines, oils) -Sudden sniffing death
-Peripheral axonopathy
Methylene chloride (paint stripper) Carbon monoxide poisoning
Toluene (glue) Non-anion gap metabolic acidosis (hippuric acid)
Nitrites -Methemoglobinemia
-Syncope
Nitrous oxide -Sedation and coma
-Vitamin B12 deficiency